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Senast redigerad av Lamento 2024-04-07 kl. 16:57.
Senast redigerad av Lamento 2024-04-07 kl. 16:57.
Kamran Abbasi, executive editor of the British Medical Journal (BMJ), also criticised Heneghan's claims about face masks because he believed his interpretation of the Danish study was inaccurate. However, Abbasi stressed that he believed it was wrong that Heneghan's opinion be marked as “false information" on Facebook because, as he wrote in the BMJ, "disagreement among experts, especially about interpretation of a study, is a common occurrence. It is the usual business of science."[23] https://en.wikipedia.org/wiki/Carl_Heneghan#COVID-19_pandemicVi kan jämföra med att kritiken av munskydd (som väl bara gällde "kirurgmunskydd" som jag minns det) också framfördes av till exempel Tegnell i Sverige (https://www.aftonbladet.se/nyheter/a/jd6jdL/trots-positiv-studie-om-munskydd-tegnell-gor-tummen-ner). Men detta nämns inte på svenska Wikipediasidan om Tegnell, som inte heller har något sånt där "avsnitt" om Covid-19 som man finner på Heneghans sida och som man brukar finna på forskare som uttryckt kritik som rör pandemin. https://sv.wikipedia.org/wiki/Anders_Tegnell
Kamran Abbasi, executive editor of the British Medical Journal (BMJ), also criticised Heneghan's claims about face masks because he believed his interpretation of the Danish study was inaccurate. However, Abbasi stressed that he believed it was wrong that Heneghan's opinion be marked as “false information" on Facebook because, as he wrote in the BMJ, "disagreement among experts, especially about interpretation of a study, is a common occurrence. It is the usual business of science."[23] https://en.wikipedia.org/wiki/Carl_Heneghan#COVID-19_pandemicVi kan jämföra med att kritiken av munskydd (som väl bara gällde "kirurgmunskydd" som jag minns det) också framfördes av till exempel Tegnell i Sverige (https://www.aftonbladet.se/nyheter/a/jd6jdL/trots-positiv-studie-om-munskydd-tegnell-gor-tummen-ner). Men detta nämns inte på svenska Wikipediasidan om Tegnell, som inte heller har något sånt där "avsnitt" om Covid-19 som man finner på Heneghans sida och som man brukar finna på forskare som uttryckt kritik som rör pandemin. https://sv.wikipedia.org/wiki/Anders_Tegnell
Recipients of two or more injections of the mRNA vaccines display a class switch to IgG4 antibodies. Abnormally high levels of IgG4 might cause autoimmune diseases, promote cancer growth, autoimmune myocarditis and other IgG 4-related diseases (IgG4-RD) in susceptible individuals.29 There are clear implications for vaccine boosting where these and similar observations8,22,30 relating to COVID-19 vaccination and the incidence of long COVID-like symptoms are substantiated, adding further to public health officials’ concerns. Understanding the persistence of viral mRNA and viral protein and their cellular pathological effects after vaccination with and without infection is clearly required. Because COVID-19 vaccines were approved without long-term safety data and might cause immune dysfunction, it is perhaps premature to assume that past SARS-CoV-2 infection is the sole common factor in long COVID. https://www1.racgp.org.au/ajgp/2024/april/long-covid-sufferers-can-take-heartMan kan notera att de skriver att Pfizers och de andras vaccin "were approved without long-term safety data". Hur är det nu med de vaccinerade svenskarna, om 98% får förhöjt IgG4 så gäller ju detta de flesta svenskar. Hur har det påverkat svenskarnas hälsa? Forskare i nu 13 st vetenskapliga tidskriftsartiklar oroar sig över detta, men i media är det tyst.
There are very few reports on the induction of IgG4 after natural infection with SARS-CoV-2. The dominant subclasses were mostly IgG1 and IgG3 (54–56). Nevertheless, a Brazilian study during the early phase of the pandemic correlated an early onset and high levels of anti-spike IgG4 antibodies with a more severe COVID-19 progression after SARS-CoV-2 infection, which might indicate a less effective antibody response (56). Additionally, Della-Torre et al. reported on a significant association of high IgG4/IgG1 ratios with poor disease outcome (57). However, in the case of a primary immune response, the causality is difficult to address, since it is also possible that a more severe infection leads to an IgG4 response and not vice versa. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847566/Och i sin studie skriver de brasilianska forskarna som Irrgang hänvisar till:
Our data also reveals an increase of IgG1 and IgG3 levels since the 8th day after symptoms onset, while IgG4 levels maintained less detectable during the study period. Surprisingly, patients who died during 8–14 and 15–21 days also showed higher anti-RBD IgG4 levels in comparison with the recovered (P < 0.05), suggesting that some life-threatening patients can elicit IgG4 to RBD antibody response in the first weeks of symptoms onset. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417219/De brasilianska forskarna undersökte 47 patienter mellan mars och juni 2020, alltså givetvis ovaccinerade, med genomsnittsålder 59 år. Omkring hälften av dessa hade diabetes och övervikt. 12 dog. Om nu IgG4 förhöjdes hos dessa som dog så kan även Covid ge förhöjt IgG4 och då är ju frågan om IgG4 är hönan eller ägget, som Irrgang et al skriver.
(2) IgG1 and IgG3 are the most prevalent antibody subclasses in the SARS-CoV-2-infected population, whereas IgG1 is the most prevalent subclass after vaccination. (3) Individuals that first had a primary SARS-CoV-2 infection and later received two doses of an mRNA vaccine exhibited a more robust capacity to neutralize Omicron than individuals who were not infected and received two doses of the Pfizer–BioNTech vaccine, which reinforces the advantage of natural immunity combined with induced immunity. (4) A class switch towards the “anti-inflammatory” antibody isotype IgG4 is induced a few weeks after the booster dose with the Pfizer–BioNTech vaccine. The levels of IgG4 remain at high levels for a long period and seem to not be affected either by a subsequent booster dose (e.g., bivalent vaccine) or by breakthrough infections. https://www.mdpi.com/1999-4915/16/2/187Hur som helst så är ju deras slutsats att "recognizing that the mRNA vaccines do not prevent reinfections [59], that all Omicron subvariants that are dominant worldwide have been shown to be less pathogenic [78,79], and that there are potential negative effects of multiple boosters on the immune system, revising the continuous booster vaccination guidelines should be considered."
There are very few reports on the induction of IgG4 after natural infection with SARS-CoV-2. The dominant subclasses were mostly IgG1 and IgG3 (54–56). Nevertheless, a Brazilian study during the early phase of the pandemic correlated an early onset and high levels of anti-spike IgG4 antibodies with a more severe COVID-19 progression after SARS-CoV-2 infection, which might indicate a less effective antibody response (56). Additionally, Della-Torre et al. reported on a significant association of high IgG4/IgG1 ratios with poor disease outcome (57). However, in the case of a primary immune response, the causality is difficult to address, since it is also possible that a more severe infection leads to an IgG4 response and not vice versa. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847566/Och i sin studie skriver de brasilianska forskarna som Irrgang hänvisar till:
Our data also reveals an increase of IgG1 and IgG3 levels since the 8th day after symptoms onset, while IgG4 levels maintained less detectable during the study period. Surprisingly, patients who died during 8–14 and 15–21 days also showed higher anti-RBD IgG4 levels in comparison with the recovered (P < 0.05), suggesting that some life-threatening patients can elicit IgG4 to RBD antibody response in the first weeks of symptoms onset. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417219/De brasilianska forskarna undersökte 47 patienter mellan mars och juni 2020, alltså givetvis ovaccinerade, med genomsnittsålder 59 år. Omkring hälften av dessa hade diabetes och övervikt. 12 dog. Om nu IgG4 förhöjdes hos dessa som dog så kan även Covid ge förhöjt IgG4 och då är ju frågan om IgG4 är hönan eller ägget, som Irrgang et al skriver.
(2) IgG1 and IgG3 are the most prevalent antibody subclasses in the SARS-CoV-2-infected population, whereas IgG1 is the most prevalent subclass after vaccination. (3) Individuals that first had a primary SARS-CoV-2 infection and later received two doses of an mRNA vaccine exhibited a more robust capacity to neutralize Omicron than individuals who were not infected and received two doses of the Pfizer–BioNTech vaccine, which reinforces the advantage of natural immunity combined with induced immunity. (4) A class switch towards the “anti-inflammatory” antibody isotype IgG4 is induced a few weeks after the booster dose with the Pfizer–BioNTech vaccine. The levels of IgG4 remain at high levels for a long period and seem to not be affected either by a subsequent booster dose (e.g., bivalent vaccine) or by breakthrough infections. https://www.mdpi.com/1999-4915/16/2/187Hur som helst så är ju deras slutsats att "recognizing that the mRNA vaccines do not prevent reinfections [59], that all Omicron subvariants that are dominant worldwide have been shown to be less pathogenic [78,79], and that there are potential negative effects of multiple boosters on the immune system, revising the continuous booster vaccination guidelines should be considered."


No significant excess mortality was observed during the first year of the pandemic (2020). However, some excess cancer mortalities were observed in 2021 after mass vaccination with the first and second vaccine doses, and significant excess mortalities were observed for all cancers and some specific types of cancer (including ovarian cancer, leukemia, prostate cancer, lip/oral/pharyngeal cancer, pancreatic cancer, and breast cancer) after mass vaccination with the third dose in 2022. https://www.cureus.com/articles/196275-increased-age-adjusted-cancer-mortality-after-the-third-mrna-lipid-nanoparticle-vaccine-dose- during-the-covid-19-pandemic-in-japan#!/Det är ju så att om mRNA-vaccinet ger turbocancer, vilket mer och mer ju antyder möjligheten av, så behöver bland annat Sveriges ledning, och även till exempel journalister och likaså sådana som Nobelstiftelsen, K.I. och andra som okritiskt promotat vaccinet och dess boostrar ta sitt ansvar.
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