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Names of substances and other identifiers
• IUPAC name: 8-bromo-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
• Chemical names: 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, 8-bromo-1-methyl-6-phenyl-; 8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
• Common name: bromazolam
• Other names: -
• CAS Registry number: 71368-80-4
Substance classification
Benzodiazepine
Chemistry and Analysis
Bromazolam is a benzodiazepine that is structurally related to flubromazolam, but differs from flubromazolam due to the absence of a fluorine in the 2-position on the phenyl ring. Bromazolam is also structurally similar to pyrazolam, where the pyridinyl group has been replaced with a phenyl group. Bromazolam is the brominated version of the internationally controlled substance alprazolam, also marketed as Xanax (Schedule IV of the 1971 United Nations Convention on Psychotropic Substances).
Pharmacology and Toxicology
Bromazolam (compound 63) was included in a study on 6-Aryl-4H-s-triazolo[4,3-a][1,4]benzodiazepines which investigated the influence of 1-substitiution on pharmacological activity. The substances included in the study were compared with triazolam, alprazolam, imipramine, chlorpromazine and diazepam.
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