köpte några flaskor från oxycalm för ett år sen ungefär, funkar väl, hmm.. inte tillräckligt iaf. jag är väldigt blyg (har en diagnos inom autismspektrat) och har enormt svårt att t.ex se folk i ögonen och så, det kanske underlättar lite (eller är det den trevliga vaniljdoften som gör det
)... sen har det ju så förbannat kort halveringstid också..
förresten..:
http://www.nature.com/npp/journal/v2.../1300021a.html
Citat:
Further studies are needed to investigate possible mechanisms by which exogenous oxytocin infusion leads to behavioral changes such as those demonstrated in this study. Early studies seemed to indicate that oxytocin and vasopressin, or at least physiologically significant amounts of these peptides, are excluded access to most regions of the CNS by the blood–brain barrier (BBB) (Ermisch et al, 1988; Meisenberg and Simmons, 1983b). However, more recently, a bidirectional saturable active transport mechanism across the BBB has been demonstrated for vasopressin (Banks et al, 1987; Zlokovic et al, 1990). The behavioral effects of peripherally circulating peptides may be indirect such as via the alteration of the BBB permeability to other substances. Oxytocin and vasopressin have been shown to affect the BBB permeability to 3H-orotic acid and an RNA precursor in some brain regions (Landgraf et al, 1977, 1978). Specific binding sites on capillary endothelial cells have been demonstrated for both peptides (Ermisch and Landgraf, 1990, Ermisch et al, 1988, 1993; Kretzchmar et al, 1986), possibly affecting BBB permeability. In addition, and of more importance, the peptide may be binding to receptors in peripheral tissues, and since these targets feed back to the CNS, this may result in the observed changes in behavior.
Another possible mechanism by which peripherally administered oxytocin and vasopressin may affect the CNS is through the formation of active fragments that may cross the BBB. Fragments of both oxytocin and vasopressin have been shown to cross the BBB and affect memory processes (de Wied et al, 1972, 1987; de Wied, 1976; de Wied and Versteeg, 1979; Walter et al, 1975; Burbach et al, 1983a,b; Tanabe et al, 1997; Rainbow et al, 1979). One promising strategy for peptide delivery to the brain is through chemical modification resulting in a peptide or fragment with favorable BBB permeability, which has important implications for the development of clinically relevant treatments.
, det fick jag utskivet när jag hade haft mjölkstockning när jag ammade mitt barn. Det gjorde att mjölken rann ut bättre. Men jag tror inte att ni fb:are kan dra den valsen för en läkare. Visst det har en viss liten lugnande effekt, men det är klart att drar man i sig hela flaskan så kanske man blir mer påverkad. Akta er killar, det kanske börjar droppa mjölk om er när ni är på krogen
