Tja!
Kratom huvudsakliga aktiva molekyl r mitragynine som omvandlas i levern(?) till 7-Hydroxymitragynine
7-Hydroxymitragynine r ca 30 gnger mer potent n mitragynine och 17 gnger mer potent n morfin!!!
7-Hydroxymitragynine Kan syntas relativt ltt frn mitragynine genom oxidering med hjlp av UV-ljus.
7% omvandlas om du bara lmnar kratomet/mitragynine i solen
Hr r en synt som lyckas omvandla 58%
Klla: https://www.reddit.com/r/TheeHive/co...tent=post_body
Min plan r att lsa 20 g kratom i 20 ml vodka tillsammans med 1-2 g citronsyra och lta det st och dra sig i solen i en vecka!
Ett annat alternativ hade varit att lsa ca 20g kratom i iso propanol sen filtrera lsningen och avdunsta ison. Sen lsa mitragynine i iso igen och bubbla syre genom lsningen samtidigt som man belyser det med en uv-lampa/solen.
Vad tror ni?
Kratom huvudsakliga aktiva molekyl r mitragynine som omvandlas i levern(?) till 7-Hydroxymitragynine
7-Hydroxymitragynine r ca 30 gnger mer potent n mitragynine och 17 gnger mer potent n morfin!!!
Citat:
7-Hydroxymitragynine is an agonist at the μ-opioid receptor with a potency, calculated using pD values, that is 30-fold higher than that of mitragynine and 17-fold higher than that of morphine, respectively.
7-Hydroxymitragynine Kan syntas relativt ltt frn mitragynine genom oxidering med hjlp av UV-ljus.
Citat:
Previous studies had suggested the plant itself produced 7-hydroxymitragynine. Sames says the team could detect it by mass spectrometry, but only at very low concentrations. Instead, the team demonstrated that sunlight and oxidizing conditions can convert about half of the mitragynine in solution to 7-hydroxymitragynine. And sunlight alone can convert about 8% of the mitragynine. Therefore, the team concluded that storage conditions can affect the potency of an extract by increasing the amount of the oxidized alkaloid.
7% omvandlas om du bara lmnar kratomet/mitragynine i solen
Hr r en synt som lyckas omvandla 58%
Citat:
7-Hydroxymitragynine: Photooxidation Under O2. A solution of mitragynine (20.0 mg, 0.0500 mmol) and rose bengal Na salt (0.5 mg) in MeOH (0.30 mL) was irradiated with a 500 halogen work lamp at 0 C under O2 atmosphere for 1.5 h. Additional MeOH (0.30 mL) and a solution of Na2S03(30.0 mg, 0.240 mmol) in water (0.27 mL) were both added, and the pink mixture was stirred vigorously at room temperature until mass spectrometry indicated the disappearance of the hydroperoxide intermediate (5 h) . The reaction was then diluted with water (2 mL) and extracted with Et20 (3 x 2 mL) . The combined organics were washed with water (2 x 2 mL) and brine (2 mL) , dried over Na2S0 , and concentrated to provide a foamy orange-brown solid (17.9 mg) . The yield of product contained in this material was determined by NMR using mesitylene as an internal standard (58% yield) .
Klla: https://www.reddit.com/r/TheeHive/co...tent=post_body
Min plan r att lsa 20 g kratom i 20 ml vodka tillsammans med 1-2 g citronsyra och lta det st och dra sig i solen i en vecka!
Ett annat alternativ hade varit att lsa ca 20g kratom i iso propanol sen filtrera lsningen och avdunsta ison. Sen lsa mitragynine i iso igen och bubbla syre genom lsningen samtidigt som man belyser det med en uv-lampa/solen.
Vad tror ni?
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Senast redigerad av LSD-Lars 2021-07-26 kl. 18:13.
Senast redigerad av LSD-Lars 2021-07-26 kl. 18:13.
