2004-06-13, 12:47
#1
Flashback bygger pepparkakshus!
2004-06-13, 22:25
#5
Men då är det bara att importera, eller? Hur mycket behöver man då för att bli skön? 
2004-06-14, 15:11
#6
2004-06-14, 23:36
#10
Yes, tjacka ett gäng i Spanien. Passa även på att köp min favvomedicin: Cod-efferalgan (Samma som panocod brus/Treo comp). Och Soñodor, visserligen bara en antihistamin men efter en 5 stycken så blir jag jättekonstig iaf 
Och eftersom KaZiber tydligen saknar all form av läsförmåga:
ACTION And MECHANISM
Benzodiazepínico Ansiolítico of short action.
It acts increasing the activity of the gamma-aminobuti'rico acid (GABA), an inhibiting neurotransmitter that is in the brain, when facilitating his union with the GABAérgico receiver. It has hipnótica, anticonvulsivante, sedative, relajante activity muscular and amnesic.
FARMACOCINÉTICA
Oral route: Its biodisponibilidad is of 86.4% (Tmax=0,65-1,45 h). He is metabolizado in the liver, eliminated mainly with it tinkles it and in smaller proportion with lees. Its half-life of elimination is of 4,5-2,8 h.
INDICATIONS
- [ ANXIETY ], [ PHOBIAS ], [ HYSTERIA ].
- [ INSOMNIA ].
DOSAGE
Oral route. Adults: 25 mg/8 h, being able to be increased the daily dose, based on the clinical answer, until a maximum of 50 mg/8 h. debilitated Ancianos and patients: 25 mg/12-24 h.
- Note: in the treatment of the insomnia the treatments superior to two or three weeks must be avoided, suggesting themselves the intermittent use of the drug during this period.
- Suspension of the treatment: In patients treated during two or more weeks of uninterrupted form, the suspension of the treatment will have to be made gradually. In general, every week usually is enough with reducing in a 25% the dose (throughout four). Nevertheless, some patients can need prolonged periods more (up to eight weeks). In hospitalized patients, the suppression can become of faster form (reducing the dose in a 10% daily).
CONTRAINDICATIONS And PRECAUTIONS
CONTRAINDICATIONS
- [ ALLERGY To BENZODIAZEPINAS ].
- SERIOUS [ MIASTENIA ]: given its muscular relajante activity, a worsening of the disease can take place, with increase of the muscular fatigabilidad.
- [ ACUTE POISONING ETILICA ], [ COMMA ] or [ SINCOPE ]; due to the depression additive on the central nervous system.
PRECAUTIONS
- [ PULMONARY DISEASE OBSTRUCTIVA CRONICA ]: given its muscular relajante activity, risk exists of which the respiratory depression is harnessed.
- [ GLAUCOMA IN NARROW ANGULO ]: it can increase intraocular the pressure given the possible anticolinérgico effect of the benzodiazepina, which can aggravate the disease.
- Historial of [ DROGODEPENDENCIA ]: the prolonged use or elevated doses of benzodiazepinas can produce psychic or physical dependency.
- [ INSUFFICIENCY HEPATICA ]: since metaboliza mainly in the liver, the dose must adjust to the degree of functional incapacity of the same one.
- [ INSUFFICIENCY RENAL ]: since it is eliminated mainly by renal route, the dose must adjust to the degree of renal functional incapacity.
ANALYTICAL INTERACCIONES/INTERFERENCIAS
The depressing of the central nervous system (alcohol, barbiturates, etc.) they can harness his sedative action.
ADVERSE EFFECTS
The adverse effects of bentazepam are, in general, frequent and moderately important. The toxicológico profile of this drug is similar to the one of the rest of ansiolíticas benzodiazepinas. In most of the cases, the adverse reactions are an prolongation of the farmacológica action and mainly affect the central nervous system. 50% of the patients experience transitory somnolencia, during the first days of treatment. Rarely the patients dealt with this medicine are themselves forced to suspend the treatment. The adverse reactions more characteristics are:
- Very frequently (> 25%): somnolencia, confusion and ataxia, specially in old and debilitated; if these symptoms persist it must reduce the dose.
- Frequently (10-25%): mareos, sedación, migraine, depression, disorientation, disfasia or disartria, reduction of the concentration, tremor, changes in the líbido one, urinary incontinencia, urinary retention, nauseas, vomits, diarrea, constipation, dryness of mouth, hypersalivation, epigástrico pain.
- Occasionally (1-9%): hepatitis, ictericia, dermatitis, urticaria, prurito, leucopenia, agranulocitosis, anemia, trombocitopenia, eosinofilia, alterations of the behavior, anterógrada amnesia, paradoxical excitation, psychosis, alterations of the vision, diplopia, nistagmo, alterations of hearing.
- Rarely (< 1%): respiratory depression, hypotension, hypertension, bradicardia, tachycardia, palpitaciones.
SPECIAL WARNINGS
With the prolonged use dependency is developed. The abrupt interruption of a treatment to usual doses can cause an abstinence syndrome (anxiety, agitation, aggressiveness, insomnia, muscular tremor, espasmo). If the treatment is with elevated doses, the abstinence syndrome can be serious (delirium and convulsions). The treatment will not be interrupted abruptly, nor will modify the doses, without consulting with the doctor (the interruption will be made gradually during 4-8 weeks). To warn the patient of the possibility of anterógrada amnesia (forgetfulness of next events).
PREGNANCY
Other benzodiazepinas cross the placenta. Well controlled suitable studies have not been made and in humans. Some studies have suggested a risk increased of congenital malformations with the use of benzodiazepinas (clordiazepóxido, diazepam) during quarterly 1er. One has attributed to syndrome of neonative abstinence (tremors and irritability) as well as neonative flaccidez and respiratory problems with the chronic use from benzodiazepinas during the pregnancy. The use of benzodiacepinas just before or during the childbirth can give rise to a syndrome in the neoborn one characterized by hipotonía, lethargy and difficulties in the lactation. Although it does not seem that the occasional use and with moderate doses tolerates special risks, rare time is urgent the use of benzodiazepinas during the pregnancy, reason why its use would be due to avoid. The possibility that a woman in treatment can remain pregnant and of interrupting the treatment in case the pregnancy has taken place must be considered.
NURSING MOTHERS
She ignores herself if bentazepam is excreted with maternal milk, however, most of the benzodiazepinas yes they excrete themselves. The neoborn ones metabolizan the benzodiazepinas more slowly, reason why the accumulation of these drugs and their metabolitos is possible reaching toxic levels (sedación, difficulties in the feeding and loss of weight). It is recommended to suspend the maternal lactancia or to avoid the administration of this medicine.
USE IN CHILDREN
The security and effectiveness of the use of bentazepam in children have not been established. Use nonrecommended in children.
USE IN OLD
The geriatrical patients can show greater sensitivity the adverse effects of the benzodiazepinas on the SNC. A retrospective study of control of cases has shown that the old ones in treatment with benzodiazepinas of short action have minor propensity to undergo falls and fractures that those in treatments with benzodiazepinas of prolonged action. It is recommended to limit the metering the effective minim and to increase it gradually, if it is necessary, to diminish the possibility of development of ataxia, mareos and excessive sedación.
EFFECTS ON THE CAPACITY TO LEAD
The benzodiazepinas tend to produce diminution of the reflections, small alterations of the psicomotriz coordination and the alert status. Therefore, the patients dealt with these drugs would have as far as possible to avoid the driving of vehicles or the handling of complex machinery specially during the first hours in the morning if she has taken the medicine at night (by the residual somnolencia). He does not take spirits.
(tacka Babelfish!)
Och eftersom KaZiber tydligen saknar all form av läsförmåga:
ACTION And MECHANISM
Benzodiazepínico Ansiolítico of short action.
It acts increasing the activity of the gamma-aminobuti'rico acid (GABA), an inhibiting neurotransmitter that is in the brain, when facilitating his union with the GABAérgico receiver. It has hipnótica, anticonvulsivante, sedative, relajante activity muscular and amnesic.
FARMACOCINÉTICA
Oral route: Its biodisponibilidad is of 86.4% (Tmax=0,65-1,45 h). He is metabolizado in the liver, eliminated mainly with it tinkles it and in smaller proportion with lees. Its half-life of elimination is of 4,5-2,8 h.
INDICATIONS
- [ ANXIETY ], [ PHOBIAS ], [ HYSTERIA ].
- [ INSOMNIA ].
DOSAGE
Oral route. Adults: 25 mg/8 h, being able to be increased the daily dose, based on the clinical answer, until a maximum of 50 mg/8 h. debilitated Ancianos and patients: 25 mg/12-24 h.
- Note: in the treatment of the insomnia the treatments superior to two or three weeks must be avoided, suggesting themselves the intermittent use of the drug during this period.
- Suspension of the treatment: In patients treated during two or more weeks of uninterrupted form, the suspension of the treatment will have to be made gradually. In general, every week usually is enough with reducing in a 25% the dose (throughout four). Nevertheless, some patients can need prolonged periods more (up to eight weeks). In hospitalized patients, the suppression can become of faster form (reducing the dose in a 10% daily).
CONTRAINDICATIONS And PRECAUTIONS
CONTRAINDICATIONS
- [ ALLERGY To BENZODIAZEPINAS ].
- SERIOUS [ MIASTENIA ]: given its muscular relajante activity, a worsening of the disease can take place, with increase of the muscular fatigabilidad.
- [ ACUTE POISONING ETILICA ], [ COMMA ] or [ SINCOPE ]; due to the depression additive on the central nervous system.
PRECAUTIONS
- [ PULMONARY DISEASE OBSTRUCTIVA CRONICA ]: given its muscular relajante activity, risk exists of which the respiratory depression is harnessed.
- [ GLAUCOMA IN NARROW ANGULO ]: it can increase intraocular the pressure given the possible anticolinérgico effect of the benzodiazepina, which can aggravate the disease.
- Historial of [ DROGODEPENDENCIA ]: the prolonged use or elevated doses of benzodiazepinas can produce psychic or physical dependency.
- [ INSUFFICIENCY HEPATICA ]: since metaboliza mainly in the liver, the dose must adjust to the degree of functional incapacity of the same one.
- [ INSUFFICIENCY RENAL ]: since it is eliminated mainly by renal route, the dose must adjust to the degree of renal functional incapacity.
ANALYTICAL INTERACCIONES/INTERFERENCIAS
The depressing of the central nervous system (alcohol, barbiturates, etc.) they can harness his sedative action.
ADVERSE EFFECTS
The adverse effects of bentazepam are, in general, frequent and moderately important. The toxicológico profile of this drug is similar to the one of the rest of ansiolíticas benzodiazepinas. In most of the cases, the adverse reactions are an prolongation of the farmacológica action and mainly affect the central nervous system. 50% of the patients experience transitory somnolencia, during the first days of treatment. Rarely the patients dealt with this medicine are themselves forced to suspend the treatment. The adverse reactions more characteristics are:
- Very frequently (> 25%): somnolencia, confusion and ataxia, specially in old and debilitated; if these symptoms persist it must reduce the dose.
- Frequently (10-25%): mareos, sedación, migraine, depression, disorientation, disfasia or disartria, reduction of the concentration, tremor, changes in the líbido one, urinary incontinencia, urinary retention, nauseas, vomits, diarrea, constipation, dryness of mouth, hypersalivation, epigástrico pain.
- Occasionally (1-9%): hepatitis, ictericia, dermatitis, urticaria, prurito, leucopenia, agranulocitosis, anemia, trombocitopenia, eosinofilia, alterations of the behavior, anterógrada amnesia, paradoxical excitation, psychosis, alterations of the vision, diplopia, nistagmo, alterations of hearing.
- Rarely (< 1%): respiratory depression, hypotension, hypertension, bradicardia, tachycardia, palpitaciones.
SPECIAL WARNINGS
With the prolonged use dependency is developed. The abrupt interruption of a treatment to usual doses can cause an abstinence syndrome (anxiety, agitation, aggressiveness, insomnia, muscular tremor, espasmo). If the treatment is with elevated doses, the abstinence syndrome can be serious (delirium and convulsions). The treatment will not be interrupted abruptly, nor will modify the doses, without consulting with the doctor (the interruption will be made gradually during 4-8 weeks). To warn the patient of the possibility of anterógrada amnesia (forgetfulness of next events).
PREGNANCY
Other benzodiazepinas cross the placenta. Well controlled suitable studies have not been made and in humans. Some studies have suggested a risk increased of congenital malformations with the use of benzodiazepinas (clordiazepóxido, diazepam) during quarterly 1er. One has attributed to syndrome of neonative abstinence (tremors and irritability) as well as neonative flaccidez and respiratory problems with the chronic use from benzodiazepinas during the pregnancy. The use of benzodiacepinas just before or during the childbirth can give rise to a syndrome in the neoborn one characterized by hipotonía, lethargy and difficulties in the lactation. Although it does not seem that the occasional use and with moderate doses tolerates special risks, rare time is urgent the use of benzodiazepinas during the pregnancy, reason why its use would be due to avoid. The possibility that a woman in treatment can remain pregnant and of interrupting the treatment in case the pregnancy has taken place must be considered.
NURSING MOTHERS
She ignores herself if bentazepam is excreted with maternal milk, however, most of the benzodiazepinas yes they excrete themselves. The neoborn ones metabolizan the benzodiazepinas more slowly, reason why the accumulation of these drugs and their metabolitos is possible reaching toxic levels (sedación, difficulties in the feeding and loss of weight). It is recommended to suspend the maternal lactancia or to avoid the administration of this medicine.
USE IN CHILDREN
The security and effectiveness of the use of bentazepam in children have not been established. Use nonrecommended in children.
USE IN OLD
The geriatrical patients can show greater sensitivity the adverse effects of the benzodiazepinas on the SNC. A retrospective study of control of cases has shown that the old ones in treatment with benzodiazepinas of short action have minor propensity to undergo falls and fractures that those in treatments with benzodiazepinas of prolonged action. It is recommended to limit the metering the effective minim and to increase it gradually, if it is necessary, to diminish the possibility of development of ataxia, mareos and excessive sedación.
EFFECTS ON THE CAPACITY TO LEAD
The benzodiazepinas tend to produce diminution of the reflections, small alterations of the psicomotriz coordination and the alert status. Therefore, the patients dealt with these drugs would have as far as possible to avoid the driving of vehicles or the handling of complex machinery specially during the first hours in the morning if she has taken the medicine at night (by the residual somnolencia). He does not take spirits.
(tacka Babelfish!)
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