Intressant info om halveringstider
"PEth production begins as soon as ethanol is consumed and peaks within 8 h after alcohol ingestion 20, 21. Once formed, it degrades very slowly, which is important for its utility as a biomarker. There are marked Individual differences in the degradation half-life of PEth. Schrock et al. 22 data indicated that subjects who had ingested a single dose of alcohol sufficient to produce a calculated BAC of 0.10 g/100 mL had a PEth elimination half-life of 3 days, and Javors et al. 23 determined a PEth half-life of 4.6 days. Helander et al. 24 found a mean half-life of 6.1 days.
The shorter half-lives tended to be found in studies involving “alcoholics” or heavy drinkers (e.g., >5 drinks per day on a regular basis). In a meta-analysis of 12 studies, Viel et al. 16 concluded that the PEth elimination half-life was between 3 and 5 days. Gnann et al. 20 documented that among “social” drinkers who were dosed with enough alcohol to “simulate extensive drinking,” the half-life varied widely, ranging between 4.5 and 10.1 days. That study involved only 11 subjects, and no measures of a central tendency were reported which would have made their findings possible to compare with other studies."
https://onlinelibrary.wiley.com/doi/10.1111/1556-4029.13874
Det betyder mao att de som dricker mycket eller ofta får kortare halveringstider. Detta kan ju vara väldigt problematiskt iom att de som då dricker mindre eller mer sällan får längre halveringstider vilket påverkar resultaten vid PEth-mätningarna på ett ofördelaktigt vis. Det blir etiskt problematiskt. Sup mer och få kortare halveringstider. Halleluja!