The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud. None of the rest show convincing evidence of ivermectin's effectiveness.https://www.bbc.co.uk/news/health-58170809
Dr Kyle Sheldrick, one of the group investigating the studies, said they had not found "a single clinical trial" claiming to show that ivermectin prevented Covid deaths that did not contain "either obvious signs of fabrication or errors so critical they invalidate the study".
Major problems included:
* The same patient data being used multiple times for supposedly different people
* Evidence that selection of patients for test groups was not random
* Numbers unlikely to occur naturally
* Percentages calculated incorrectly
* Local health bodies unaware of the studies
The scientists in the group - Gideon Meyerowitz-Katz, Dr James Heathers, Dr Nick Brown and Dr Sheldrick - each have a track record of exposing dodgy science. They've been working together remotely on an informal and voluntary basis during the pandemic.
They formed a group looking deeper into ivermectin studies after biomedical student Jack Lawrence spotted problems with an influential study from Egypt. Among other issues, it contained patients who turned out to have died before the trial started. It has now been retracted by the journal that published it.
The group of independent scientists examined virtually every randomised controlled trial (RCT) on ivermectin and Covid - in theory the highest quality evidence - including all the key studies regularly cited by the drug's promoters.
RCTs involve people being randomly chosen to receive either the drug which is being tested or a placebo - a dummy drug with no active properties.
The team also looked at six particularly influential observational trials. This type of trial looks at what happens to people who are taking the drug anyway, so can be biased by the types of people who choose to take the treatment.Jag uppmanar som sagt alla - även dummerjönskungen - att läsa artikeln. Den skit som han sitter och spyr ur sig dagligen kommer alltså från forskning som är rent fusk, lögner och antivaxxar-patraskeri.
[b]Out of a total of 26 studies examined, there was evidence in five that the data may have been faked - for example they contained virtually impossible numbers or rows of identical patients copied and pasted.
In a further five there were major red flags - for example, numbers didn't add up, percentages were calculated incorrectly or local health bodies weren't aware they had taken place.
On top of these flawed trials, there were 14 authors of studies who failed to send data back. The independent scientists have flagged this as a possible indicator of fraud.
...
A recent study in Lebanon was found to have blocks of details of 11 patients that had been copied and pasted repeatedly - suggesting many of the trial's apparent patients didn't really exist.
...
Another study from Iran seemed to show that ivermectin prevented people dying from Covid.
But the scientists who investigated it found issues. The records of how much iron was in patients' blood contained numbers in a sequence that was unlikely to come up naturally.
And the patients given the placebo turned out to have had much lower levels of oxygen in their blood before the trial started than those given ivermectin. So they were already sicker and statistically more likely to die.
The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud. None of the rest show convincing evidence of ivermectin's effectiveness.https://www.bbc.co.uk/news/health-58170809
Dr Kyle Sheldrick, one of the group investigating the studies, said they had not found "a single clinical trial" claiming to show that ivermectin prevented Covid deaths that did not contain "either obvious signs of fabrication or errors so critical they invalidate the study".
Major problems included:
* The same patient data being used multiple times for supposedly different people
* Evidence that selection of patients for test groups was not random
* Numbers unlikely to occur naturally
* Percentages calculated incorrectly
* Local health bodies unaware of the studies
The scientists in the group - Gideon Meyerowitz-Katz, Dr James Heathers, Dr Nick Brown and Dr Sheldrick - each have a track record of exposing dodgy science. They've been working together remotely on an informal and voluntary basis during the pandemic.
They formed a group looking deeper into ivermectin studies after biomedical student Jack Lawrence spotted problems with an influential study from Egypt. Among other issues, it contained patients who turned out to have died before the trial started. It has now been retracted by the journal that published it.
The group of independent scientists examined virtually every randomised controlled trial (RCT) on ivermectin and Covid - in theory the highest quality evidence - including all the key studies regularly cited by the drug's promoters.
RCTs involve people being randomly chosen to receive either the drug which is being tested or a placebo - a dummy drug with no active properties.
The team also looked at six particularly influential observational trials. This type of trial looks at what happens to people who are taking the drug anyway, so can be biased by the types of people who choose to take the treatment.Jag uppmanar som sagt alla - även dummerjönskungen - att läsa artikeln. Den skit som han sitter och spyr ur sig dagligen kommer alltså från forskning som är rent fusk, lögner och antivaxxar-patraskeri.
[b]Out of a total of 26 studies examined, there was evidence in five that the data may have been faked - for example they contained virtually impossible numbers or rows of identical patients copied and pasted.
In a further five there were major red flags - for example, numbers didn't add up, percentages were calculated incorrectly or local health bodies weren't aware they had taken place.
On top of these flawed trials, there were 14 authors of studies who failed to send data back. The independent scientists have flagged this as a possible indicator of fraud.
...
A recent study in Lebanon was found to have blocks of details of 11 patients that had been copied and pasted repeatedly - suggesting many of the trial's apparent patients didn't really exist.
...
Another study from Iran seemed to show that ivermectin prevented people dying from Covid.
But the scientists who investigated it found issues. The records of how much iron was in patients' blood contained numbers in a sequence that was unlikely to come up naturally.
And the patients given the placebo turned out to have had much lower levels of oxygen in their blood before the trial started than those given ivermectin. So they were already sicker and statistically more likely to die.
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