Citat:
Ursprungligen postat av
Lamento
Du har rätt, jag tar tillbaka det och ber om ursäkt, jag googlade första citatet som du angav som
"Skyddet mot död är betydligt högre än 94% för Pfizer och 71% för AstraZeneca.”,
(FB) Dödligt virus från Kina orsakar panik (SARS-CoV-2, COVID-19)
Men hittade det sen:
"Skyddet mot död ÄR betydligt högre än 94% för Pfizer och 71% för AstraZeneca."
(FB) 70 % av de coronadöda är fullvaccinerade (under 1-24 september /mod)
Ja, svårt att veta vad som är vad numera.
Ja, om en ny variant inte utnyttjar ovaccinerades brist på lgG4 
Mixtrail 8x7b instruct can ge dig lite ledtrådar:
"USER
What does high Ig4 mean for an antigen, concerning the immune system?
AI
IgG and IgM are the antibodies that are typically associated with an active immune response against an antigen, while IgA and IgE have other specific functions. IgD is found on the surface of B cells and plays a role in their activation.
IgG4 is a subclass of IgG and has some unique properties compared to other IgG subclasses. It does not activate complement, and it can form large complexes with antigens that do not cause inflammation or tissue damage. IgG4 also has the ability to exchange half-molecules with other IgG4 antibodies, which can lead to the formation of bispecific antibodies that bind to two different epitopes on an antigen.
A high level of IgG4 response could indicate a chronic immune response or an ongoing exposure to a specific antigen. It has been associated with some autoimmune diseases and certain types of allergies, but it can also be seen in normal immune responses to persistent antigens such as those present in some vaccines or during infections with helminths (parasitic worms). However, the interpretation of IgG4 levels should be done with caution and in conjunction with other clinical and laboratory findings.
USER
can it be interpreted as the immune system is tolerating the antigen?
AI
A high level of IgG4 response can indicate that the immune system is tolerating an antigen, but this interpretation should be made with caution.
IgG4 antibodies are associated with a type of immune response known as a "T-cell-independent" response, which is characterized by the absence of T-cell activation and inflammation. This type of response can occur in situations where the antigen is not harmful or when the immune system has been exposed to the antigen for a long time, leading to a state of tolerance.
In some cases, high levels of IgG4 have been associated with a regulatory or protective role, where the immune system is actively tolerating the antigen to prevent an excessive and damaging response. However, IgG4 can also be produced in response to chronic inflammation or allergic reactions, so its presence alone does not necessarily indicate tolerance.
Therefore, the interpretation of high IgG4 levels should be made with caution and in the context of other clinical and laboratory findings, such as the presence of other antibodies, symptoms, and medical history."