Den mutation E484K som finns i den Sydafrikanska varianten SA B1351 har också upptäckts i
den Brasilianska varianten B11248 av ett Japanskt lab.
Eric Feigl-Ding har sammanställt intressant information om E484K.
In a recent study by @jbloom_lab, E484 mutation (inside the #SARSCoV2’s spike’s critical receptor binding domain) seemed to escape neutralizing antibodies—bad.
Escaping neutralizing antibodies could mean some convalescent plasma, some antibody drugs, and maybe even vaccines could be disrupted a little.
https://twitter.com/DrEricDing/status/1348607329881763841
Eric Feigl-Dings slutsats är långt ifrån den Svenska modellen (Pressa ner kurvan strax under sjukvårdens max kapacitet):
Many experts think maybe it’s the use of synthetic monoclonal antibody drugs and maybe CP in a few chronically sick immunocompromised person long term that drove the evolution of the virus in such ways to adapt.
This is why we must end the pandemic w/ #ZeroCovid to win this.