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Ursprungligen postat av
aw
Soo Aleman sa till att börja med att man inte visste säkert ännu vad som gäller för COVID-19, men att:
1) T-cellsimmunitet (på den nivå de observerade) brukar innebära immunitet, och
2) en längre immunitet än antikroppar.
Vid SARS och MERS så har T-cellsimmunitet bestått i tio år eller mer. Även när antikropparna försvunnit tidigare.
It usually means that the body will produce antibodies, specifically IgA in the case of SARS-COV-2 which has the largest mitigating effect but disappears the fastest (which is why IgG and IgM are the measured antibodies in antibody assay, although I’ve heard that IgA antibodies apparently survive longer in the mucosal membranes. This could also be an antibody response missed by these tests). However, if their speculation that the virus is defeated at the T-Cell level without producing antibodies is true, this will mean that immunity is not possible at this current point. T-Cells will not prevent the virus from attacking and infecting cells, they are simply the first line of defence when this happens — and they will not have committed an antibody response to memory. My earlier statements that the immunity system is something that ebbs and wanes in strength is still true — factors such as the seasons and stress, diet, etc. all affect the strength of the immune system.
The key point in SARS-COV-1 is that the infection was beaten back by antibodies. T-Cells alone didn’t beat this back without committing antibodies to memory. The way it would beat this virus back a second time is by reproducing these antibodies. This is where the immunity to a virus comes from, as antibodies do naturally wane in the blood over time (although this varies from virus to virus).