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TimmieStark
Tack!
Betyder det här att det inte spelar någon roll hur många virus man blir infekterad med?
Man blir lika allvarligt eller inte allvarligt sjuk oavsett?
Har jag missförstått?
”We analyzed the viral load in nasal and throat swabs obtained from the 17 symptomatic patients in relation to day of onset of any symptoms (Figure 1C). Higher viral loads (inversely related to Ct value) were detected soon after symptom onset, with higher viral loads detected in the nose than in the throat.
Our analysis suggests that the viral nucleic acid shedding pattern of patients infected with SARS-CoV-2 resembles that of patients with influenza4 and appears different from that seen in patients infected with SARS-CoV.3 The viral load that was detected in the asymptomatic patient was similar to that in the symptomatic patients, which suggests the transmission potential of asymptomatic or minimally symptomatic patients.”
Källa:
https://www.nejm.org/doi/full/10.1056/NEJMc2001737
Du har missförstått.
Här finns fler belägg för att storleken på virusdosen har betydelse för hur allvarligt sjuk man blir av covid.
"Late last month, when the virus had infected 80,000 worldwide, the Los Angles Times reported that 3,387 health workers in China had contracted COVID-19. Among the first health care professionals to die were two doctors, just 29 and 34 years old.
As a whole, doctors and nurses are more exposed to the coronavirus just by nature of working with the ill. But research also suggests that how much virus they’re exposed to matters, too. As Anna Yeung-Cheung, a virologist at Manhattanville College, told Slate‘s Shannon Palus in February, the reason a young doctor died of COVID-19 is, in part, because he was a doctor. “It’s a dosage thing,” she said.
While this hasn’t been tested in human trials for obvious ethical reasons, we do have some information about how other coronaviruses affect animals: Researchers have found the more of a virus the animal is exposed to, the worse disease it develops. “When we infect animals with related coronaviruses with a lower dose of viral particles, they don’t become as ill as if we infect them with a higher dose of viral particles,” Graham says. “So there is a dose-dependent response to illness.” The animal models are “a pretty good indicator,” she says, of why health professionals who work directly with infected people are experiencing more severe illness."
https://www.motherjones.com/politics/2020/03/coronavirus-immunity-questions-answered/
