Citat:
Därför att det är en mer beprövad teknik än mRNA-vaccinerna.
Från Sputnik-vaccinets internet-sida:
ADENOVIRAL VACCINESJag tänker att under den tid som Gamaleya har sysslat med adenovektor-vacciner, så borde eventuella långsiktiga biverkningar ha upptäckts. MRNA-vacciner har inte använts lika länge.
Adenoviral vectors are considered extremely safe, and are some of the easiest to engineer. Vectors are viruses that have had the gene responsible for replication removed. Therefore, they no longer pose any threat of infection. Scientists use vectors to transport genetic material from a different virus -the one that is being vaccinated against -into a human cell.
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HUMAN ADENOVIRUSES REPRESENT A WELL-STUDIED TECHNOLOGY PLATFORM WITH SUBSTANTIATED, LONG-TERM SAFETY
More than 20,000 people around the world have participated in clinical trials on drugs that use adenovirus vectors.
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Human adenovirus-based drugs have been widely used for more than 50 years.
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SUCCESSFUL EXPERIENCE AT THE GAMALEYA CENTER
Scientists from the Gamaleya Center have been working on adenoviral vector-based vaccines since the 1980s, and now lead the world in developing these types of vaccines.
Another adenoviral vector-based vaccine against Middle East Respiratory Syndrome (MERS) is in the advanced stages of clinical trials. Many other COVID-19 vaccine candidates also do use adenoviral vectors, but none uses the two-vector platform developed by the Gamaleya Center.
During the vaccine creation process, a gene with the code of a coronavirus S (spike) protein is inserted into an adenoviral vector. This inserted component is safe for the human body, but still helps the immune system to react and produce the antibodies that protect us from infection.
Using adenovirus vectors, scientists at the Gamaleya Center successfully created, and were issued the Russian Federation Ministry of Healthcare certificate of registration for, a vaccine against the Ebola fever that incorporates adenovirus vectors.