Dödligt virus från Kina orsakar panik (SARS-CoV-2, COVID-19)

"The doses used in cell culture would require 104 larger doses in humans based on this data, which does not look promising as an effective treatment for COVID-19.[86][87] Such high doses of ivermectin are not covered by the current human-use approvals of the drug and could be dangerous, as the likely antiviral mechanism of action is the suppression of a host cellular process,[87] specifically the inhibition of nuclear transport by importin α/β1.[88] Moreover, cell culture experiments also showed promise for ivermectin treating Dengue, but later failed in animal models.[86]

On 10 April 2020, the FDA issued guidance to not use ivermectin intended for animals as treatment for COVID-19 in humans.[89]

A preprint published in April 2020 claimed benefits of ivermectin in the treatment of COVID-19, but it was a retrospective study based on questionable hospital data from Surgisphere and was withdrawn at the end of May. The preprint led to several government agencies in Latin America recommending ivermectin as a COVID-19 treatment; these recommendations were later denounced by the regional WHO office.[90]"