Fler långvariga alt. kroniska problem som väntar runt hörnet efter en genomgången coronainfektion?
More than just smell -COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
https://www.medrxiv.org/content/10.1101/2020.05.04.20090902v1.full.pdf
"Our study confirms and substantially extends previous reports showing that smell loss and taste loss are associated with COVID-19. Similar to other recent studies (Bagheri et al., 2020; Chen et al., 2020; Gane et al., 2020; Giacomelli et al., 2020; Haldrup et al., 2020; Hopkins et al., 2020; Lechien et al., 2020a, 2020b; Mao et al., 2020; Menni et al., 2020; Moein et al., 2020; Yan et al., 2020a, 2020b), we find that the majority of our participants with COVID-19 reports a severe reduction in the ability to smell as compared to before the onset of that disease. Notably, this smell loss was not associated with self-reported nasal obstruction, consistent with anecdotal reports. Further, we find that qualitative changes in smell (smell distortionsor phantoms) were relatively rare. We found that taste, and to a lesser degree chemesthesis, were also significantly impaired for individuals with COVID-19.
Together, these results suggest that COVID-19 broadly impacts chemosensory function across multiple sensory modalities, and that disruption of these maybe a possible indicator of COVID-19."
Bakgrund och kontext.
CHEMOSENSORY FUNCTION AND DYSFUNCTION :
[Critical Reviews in Oral Biology & Medicine 9(3) 267-291(1998)]
"Taste and smell are fundamental sensory systems essential in nutrition and food selection,for the hedonic and sensory experience of food,for efficient metabolism, and, in general, for the maintenance of a good quality of life.The gustatory and olfactory systems demonstrate adiversity of transduction mechanisms,and during the last decade,considerable progress has been made toward ourunderstanding of the basic mechanisms of taste and smell.Understanding normal chemosensory function helps clarify the molecular events that underlie taste and smell disorders. At least 2,000,000 Americans suffer from chemosensory disorders-a number that is likely to grow as the aging segment of the population increases."
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Although diagnosis of taste and smell disorders has improved considerably over the last two decades,treatment of these disorders is still limited to conditions with discernible and reversible causes."
https://journals.sagepub.com/doi/pdf/10.1177/10454411980090030201