Citat:
Ursprungligen postat av
outoftheblue
Det tycks ha med mastceller och histamin att göra. D-vitamin stabiliserar mastceller så att de inte släpper ut sina substanser i onödan.
...Mast cell histamine has been implicated in the pathophysiology of COVID-19 as a regulator of proinflammatory, fibrotic, and thrombogenic processes. Consequently, mast cell histamine and its receptors represent promising pharmacological targets. At the same time, nutritional modulation of immune system function has been proposed and is being investigated for the prevention of COVID-19 or as an adjunctive strategy combined with conventional therapy. Several studies indicate that several immunonutrients can regulate mast cell activity to reduce the de novo synthesis and/or release of histamine and other mediators that are considered to mediate, at least in part, the complex pathophysiology present in COVID-19...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537261/
...Vitamin D seems to preserve the stability of mast cells, possibly by maintaining the expression of vitamin D receptors. In a vitamin D-deficient environment, mast cell activation occurs automatically, even in the absence of specific triggering [51]. In addition, it has been shown that vitamin D inhibits histamine release from mast cell activation including IgE-mediated activation [52]...
Så det blir till att käka D-vitamin mot hösnuva med. 100 mikrogram per dag säger livsmedelsverket är OK.
Det var intressant! Har pollenallergi o har käkat 5000iu dagligen under 3 år. Ja, pollenallergin har inte varit lika jobbig som vanligt. Men varierar år till år så svårt dra slutsatser enkelt. Behöver ändå ta antihistamin då o då.
Man kan ta enkla blodprov o mäta sin nivå av Vitamin D.
"Conclusion: Vitamin D levels were found to be low in subjects with allergic rhinitis. The levels of Vitamin D correlated with the severity of disease. There was highly significant reduction in the total nasal symptom score after supplementation. Thus Vitamin D supplementation alters the course of Allergic Rhinitis towards clinical improvement."
https://erj.ersjournals.com/content/46/suppl_59/PA2559
